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Neuregulin-4 Is a Survival Factor for Colon Epithelial Cells both in Culture and in Vivo
Expression of the ErbB4 tyrosine kinase is elevated in colonic epithelial cells during inflammatory bowel disease, whereas ErbB4 overexpression in cultured colonocytes blocks TNF-induced apoptosis in a ligand-dependent manner. Together, these observations suggest that ErbB4 induction may be a protec...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501086/ https://ncbi.nlm.nih.gov/pubmed/23033483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.400846 |
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