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A Rapid, Comprehensive Liquid Chromatography-Mass Spectrometry (LC-MS)-based Survey of the Asp Isomers in Crystallins from Human Cataract Lenses

Cataracts are caused by clouding of the eye lens and may lead to partial or total loss of vision. The mechanism of cataract development, however, is not well understood. It is thought that abnormal aggregates of lens proteins form with age, causing loss of lens clarity and development of the catarac...

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Bibliographische Detailangaben
Hauptverfasser: Fujii, Norihiko, Sakaue, Hiroaki, Sasaki, Hiroshi, Fujii, Noriko
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501074/
https://ncbi.nlm.nih.gov/pubmed/23007399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.399972
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