ATG8 Family Proteins Act as Scaffolds for Assembly of the ULK Complex: SEQUENCE REQUIREMENTS FOR LC3-INTERACTING REGION (LIR) MOTIFS

Autophagy is a lysosome-dependent degradation system conserved among eukaryotes. The mammalian Atg1 homologues, Unc-51 like kinase (ULK) 1 and 2, are multifunctional proteins with roles in autophagy, neurite outgrowth, and vesicle transport. The mammalian ULK complex involved in autophagy consists o...

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Autors principals: Alemu, Endalkachew Ashenafi, Lamark, Trond, Torgersen, Knut Martin, Birgisdottir, Aasa Birna, Larsen, Kenneth Bowitz, Jain, Ashish, Olsvik, Hallvard, Øvervatn, Aud, Kirkin, Vladimir, Johansen, Terje
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3501051/
https://ncbi.nlm.nih.gov/pubmed/23043107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.378109
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