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Opposite Effects of KCTD Subunit Domains on GABA(B) Receptor-mediated Desensitization
GABA(B) receptors assemble from principle and auxiliary subunits. The principle subunits GABA(B1) and GABA(B2) form functional heteromeric GABA(B(1,2)) receptors that associate with homotetramers of auxiliary KCTD8, -12, -12b, or -16 (named after their K(+) channel tetramerization domain) subunits....
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3501043/ https://ncbi.nlm.nih.gov/pubmed/23035119 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.412767 |
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