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Structural and biochemical characterization of the inhibitor complexes of XMRV protease

Interactions between the protease (PR) encoded by the xenotropic murine leukemia virus-related virus (XMRV) and a number of potential inhibitors have been investigated by biochemical and structural techniques. It was observed that several inhibitors used clinically against HIV PR exhibit nanomolar o...

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Detalhes bibliográficos
Main Authors: Li, Mi, Gustchina, Alla, Matúz, Krisztina, Tözsér, Jozsef, Namwong, Sirilak, Goldfarb, Nathan E., Dunn, Ben M., Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500906/
https://ncbi.nlm.nih.gov/pubmed/21951660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2011.08364.x
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