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Crystal structures of inhibitor complexes of human T cell leukemia virus (HTLV-1) protease

Human T-cell leukemia virus type 1 (HTLV-1) is a retrovirus associated with several serious diseases, such as adult T-cell leukemia and tropical spastic paraparesis/myelopathy. For a number of years, the protease (PR) encoded by HTLV-1 has been a target for designing antiviral drugs, but that effort...

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Main Authors: Satoh, Tadashi, Li, Mi, Nguyen, Jeffrey-Tri, Kiso, Yoshiaki, Gustchina, Alla, Wlodawer, Alexander
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918672/
https://ncbi.nlm.nih.gov/pubmed/20600105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.06.052
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