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Crystal structure of XMRV protease differs from the structures of other retropepsins

Using energy and density guided Rosetta refinement to improve molecular replacement, we have determined the crystal structure of the protease (PR) encoded by xenotropic murine leukemia virus-related virus (XMRV). Despite overall similarity of XMRV PR to other retropepsins, the topology of its dimer...

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Detalhes bibliográficos
Main Authors: Li, Mi, DiMaio, Frank, Zhou, Dongwen, Gustchina, Alla, Lubkowski, Jacek, Dauter, Zbigniew, Baker, David, Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058223/
https://ncbi.nlm.nih.gov/pubmed/21258323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1964
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