Crizotinib for the Treatment of ALK-Rearranged Non-Small Cell Lung Cancer: A Success Story to Usher in the Second Decade of Molecular Targeted Therapy in Oncology

Crizotinib, an ALK/MET/ROS1 inhibitor, was approved by the U.S. Food and Drug Administration for the treatment of anaplastic lymphoma kinase (ALK)-rearranged non-small cell lung cancer (NSCLC) in August 2011, merely 4 years after the first publication of ALK-rearranged NSCLC. The crizotinib approval...

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Bibliografiske detaljer
Main Authors: Ou, Sai-Hong Ignatius, Bartlett, Cynthia Huang, Mino-Kenudson, Mari, Cui, Jean, Iafrate, A. John
Format: Artigo
Sprog:Inglês
Udgivet: AlphaMed Press 2012
Fag:
Academia-Pharma Intersect
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500356/
https://ncbi.nlm.nih.gov/pubmed/22989574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2012-0311
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