Hyaluronan (HA) Interacting Proteins RHAMM and Hyaluronidase Impact Prostate Cancer Cell Behavior and Invadopodia Formation in 3D HA-Based Hydrogels

To study the individual functions of hyaluronan interacting proteins in prostate cancer (PCa) motility through connective tissues, we developed a novel three-dimensional (3D) hyaluronic acid (HA) hydrogel assay that provides a flexible, quantifiable, and physiologically relevant alternative to curre...

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Bibliographic Details
Main Authors: Gurski, Lisa A., Xu, Xian, Labrada, Lyana N., Nguyen, Ngoc T., Xiao, Longxi, van Golen, Kenneth L., Jia, Xinqiao, Farach-Carson, Mary C.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500332/
https://ncbi.nlm.nih.gov/pubmed/23166824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050075
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