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Targeting wild-type Erythrocyte receptors for Plasmodium falciparum and vivax Merozoites by Zinc Finger Nucleases In- silico: Towards a Genetic Vaccine against Malaria

BACKGROUND: Malaria causes immense human morbidity and mortality globally. The plasmodium species vivax and falciparum cause over 75 % clinical malaria cases. Until now, gene-based strategies against malaria have only been applied to plasmodium species and their mosquito-vector. Merozoites of these...

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Detalhes bibliográficos
Main Authors: Kajumbula, Henry, Byarugaba, Wilson, Wayengera, Misaki
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3500210/
https://ncbi.nlm.nih.gov/pubmed/22938508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-0556-10-8
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