TGF-β and retinoic acid induce miR-10a, which targets Bcl-6 and constrains helper T cell plasticity

Distinct CD4(+) T cell subsets are critical for host defense and immunoregulation. While these subsets can behave as terminally differentiated lineages, elements of plasticity are increasingly recognized. MicroRNAs are one factor that controls stability and plasticity. Herein, we report that miR-10a...

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Detalhes bibliográficos
Main Authors: Takahashi, Hayato, Kanno, Tomohiko, Nakayamada, Shingo, Hirahara, Kiyoshi, Sciumè, Giuseppe, Muljo, Stefan A., Kuchen, Stefan, Casellas, Rafael, Wei, Lai, Kanno, Yuka, O'Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499969/
https://ncbi.nlm.nih.gov/pubmed/22544395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2286
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