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Quantifying harmful mutations in human populations
A number of previous studies suggested the presence of deleterious amino acid altering nonsynonymous single-nucleotide polymorphisms (nSNPs) in human populations. However, the proportions of deleterious nSNPs among rare and common variants are not known. To estimate these, >77 000 SNPs from human...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499755/ https://ncbi.nlm.nih.gov/pubmed/22510852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.68 |
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