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Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and results

Various modeling methods have been proposed to estimate the potential predictive ability of polygenic risk variants that predispose to various common diseases. However, it is unknown whether differences between them affect their conclusions on predictive ability. We reviewed input parameters, assump...

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Bibliografische gegevens
Hoofdauteurs: Kundu, Suman, Karssen, Lennart C, Janssens, A Cecile JW
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499740/
https://ncbi.nlm.nih.gov/pubmed/22643180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.89
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