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Analytical and simulation methods for estimating the potential predictive ability of genetic profiling: a comparison of methods and results
Various modeling methods have been proposed to estimate the potential predictive ability of polygenic risk variants that predispose to various common diseases. However, it is unknown whether differences between them affect their conclusions on predictive ability. We reviewed input parameters, assump...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499740/ https://ncbi.nlm.nih.gov/pubmed/22643180 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.89 |
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