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Estimating the predictive ability of genetic risk models in simulated data based on published results from genome-wide association studies

Background: There is increasing interest in investigating genetic risk models in empirical studies, but such studies are premature when the expected predictive ability of the risk model is low. We assessed how accurately the predictive ability of genetic risk models can be estimated in simulated dat...

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Detalhes bibliográficos
Main Authors: Kundu, Suman, Mihaescu, Raluca, Meijer, Catherina M. C., Bakker, Rachel, Janssens, A. Cecile J. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4056181/
https://ncbi.nlm.nih.gov/pubmed/24982668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2014.00179
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