A Steep Radioiodine Dose Response Scalable to Humans in Sodium Iodide Symporter (NIS) Mediated Radiovirotherapy for Prostate Cancer

The sodium iodide symporter (NIS) directs the uptake and concentration of iodide in thyroid cells. We have extended the use of NIS-mediated radioiodine therapy to prostate cancer. We have developed a prostate tumor specific conditionally replicating adenovirus (CRAd) that expresses hNIS (Ad5PB_RSV-N...

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Hlavní autoři: Trujillo, Miguel A., Oneal, Michael J., McDonough, Samantha, Qin, Rui, Morris, John C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499676/
https://ncbi.nlm.nih.gov/pubmed/23037808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2012.68
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