A Steep Radioiodine Dose Response Scalable to Humans in Sodium Iodide Symporter (NIS) Mediated Radiovirotherapy for Prostate Cancer

The sodium iodide symporter (NIS) directs the uptake and concentration of iodide in thyroid cells. We have extended the use of NIS-mediated radioiodine therapy to prostate cancer. We have developed a prostate tumor specific conditionally replicating adenovirus (CRAd) that expresses hNIS (Ad5PB_RSV-N...

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Bibliografiske detaljer
Main Authors: Trujillo, Miguel A., Oneal, Michael J., McDonough, Samantha, Qin, Rui, Morris, John C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499676/
https://ncbi.nlm.nih.gov/pubmed/23037808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2012.68
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