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Identification of HIV-1 Inhibitors Targeting The Nucleocapsid Protein
The HIV-1 nucleocapsid (NC) is a RNA/DNA binding protein encoded within the Gag polyprotein, which is critical for the selection and chaperoning of viral genomic RNA during virion assembly. RNA/DNA binding occurs through a highly conserved zinc-knuckle motif present in NC. Given the necessity of NC-...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499629/ https://ncbi.nlm.nih.gov/pubmed/22587465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm201442t |
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