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NMR in the Analysis of Functional Chemokine Interactions and Drug Discovery

The involvement of chemokines and chemokine receptors in a great variety of pathological indications underscores their utility as therapeutic targets. In general, chemokine-mediated migration and signaling requires three distinct interactions: self-association, glycosaminoglycan (GAG) binding, and a...

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Bibliografische gegevens
Hoofdauteurs: Ziarek, Joshua J., Volkman, Brian F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499625/
https://ncbi.nlm.nih.gov/pubmed/23166561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2012.04.003
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