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NMR in the Analysis of Functional Chemokine Interactions and Drug Discovery
The involvement of chemokines and chemokine receptors in a great variety of pathological indications underscores their utility as therapeutic targets. In general, chemokine-mediated migration and signaling requires three distinct interactions: self-association, glycosaminoglycan (GAG) binding, and a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3499625/ https://ncbi.nlm.nih.gov/pubmed/23166561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ddtec.2012.04.003 |
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