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Role of Human Sec63 in Modulating the Steady-State Levels of Multi-Spanning Membrane Proteins

The Sec61 translocon of the endoplasmic reticulum (ER) membrane forms an aqueous pore, allowing polypeptides to be transferred across or integrated into membranes. Protein translocation into the ER can occur co- and posttranslationally. In yeast, posttranslational translocation involves the heptamer...

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Detalhes bibliográficos
Main Authors: Mades, Andreas, Gotthardt, Katherina, Awe, Karin, Stieler, Jens, Döring, Tatjana, Füser, Sabine, Prange, Reinhild
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499540/
https://ncbi.nlm.nih.gov/pubmed/23166619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049243
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