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Role of Human Sec63 in Modulating the Steady-State Levels of Multi-Spanning Membrane Proteins

The Sec61 translocon of the endoplasmic reticulum (ER) membrane forms an aqueous pore, allowing polypeptides to be transferred across or integrated into membranes. Protein translocation into the ER can occur co- and posttranslationally. In yeast, posttranslational translocation involves the heptamer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mades, Andreas, Gotthardt, Katherina, Awe, Karin, Stieler, Jens, Döring, Tatjana, Füser, Sabine, Prange, Reinhild
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499540/
https://ncbi.nlm.nih.gov/pubmed/23166619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049243
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