HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

BACKGROUND: Although recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular underpinnings of normal stem cell function remain poorly understood. The high mobility group A1 (HMGA1) gene is highly expressed in hESCs and poorly diffe...

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Autors principals: Shah, Sandeep N., Kerr, Candace, Cope, Leslie, Zambidis, Elias, Liu, Cyndi, Hillion, Joelle, Belton, Amy, Huso, David L., Resar, Linda M. S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499526/
https://ncbi.nlm.nih.gov/pubmed/23166588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048533
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