HMGA1 Reprograms Somatic Cells into Pluripotent Stem Cells by Inducing Stem Cell Transcriptional Networks

BACKGROUND: Although recent studies have identified genes expressed in human embryonic stem cells (hESCs) that induce pluripotency, the molecular underpinnings of normal stem cell function remain poorly understood. The high mobility group A1 (HMGA1) gene is highly expressed in hESCs and poorly diffe...

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Detalhes bibliográficos
Main Authors: Shah, Sandeep N., Kerr, Candace, Cope, Leslie, Zambidis, Elias, Liu, Cyndi, Hillion, Joelle, Belton, Amy, Huso, David L., Resar, Linda M. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499526/
https://ncbi.nlm.nih.gov/pubmed/23166588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048533
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