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Lessons from Model Organisms: Phenotypic Robustness and Missing Heritability in Complex Disease

Genetically tractable model organisms from phages to mice have taught us invaluable lessons about fundamental biological processes and disease-causing mutations. Owing to technological and computational advances, human biology and the causes of human diseases have become accessible as never before....

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Bibliographic Details
Main Authors: Queitsch, Christine, Carlson, Keisha D., Girirajan, Santhosh
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499356/
https://ncbi.nlm.nih.gov/pubmed/23166511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003041
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