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The Origin of Minus-end Directionality and Mechanochemistry of Ncd Motors

Adaptation of molecular structure to the ligand chemistry and interaction with the cytoskeletal filament are key to understanding the mechanochemistry of molecular motors. Despite the striking structural similarity with kinesin-1, which moves towards plus-end, Ncd motors exhibit minus-end directiona...

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Bibliografiske detaljer
Main Authors: Jana, Biman, Hyeon, Changbong, Onuchic, José N.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499263/
https://ncbi.nlm.nih.gov/pubmed/23166486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002783
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