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The Origin of Minus-end Directionality and Mechanochemistry of Ncd Motors

Adaptation of molecular structure to the ligand chemistry and interaction with the cytoskeletal filament are key to understanding the mechanochemistry of molecular motors. Despite the striking structural similarity with kinesin-1, which moves towards plus-end, Ncd motors exhibit minus-end directiona...

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Detalhes bibliográficos
Main Authors: Jana, Biman, Hyeon, Changbong, Onuchic, José N.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499263/
https://ncbi.nlm.nih.gov/pubmed/23166486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002783
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