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The Origin of Minus-end Directionality and Mechanochemistry of Ncd Motors

Adaptation of molecular structure to the ligand chemistry and interaction with the cytoskeletal filament are key to understanding the mechanochemistry of molecular motors. Despite the striking structural similarity with kinesin-1, which moves towards plus-end, Ncd motors exhibit minus-end directiona...

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Autori principali: Jana, Biman, Hyeon, Changbong, Onuchic, José N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499263/
https://ncbi.nlm.nih.gov/pubmed/23166486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002783
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