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Regulation of the production of secretory proteins: Intracellular degradation of newly synthesized “defective” collagen

Confluent cultures of human fetal lung fibroblasts degrade approximately 10% of their newly synthesized collagen within the cell prior to secretion. This basal level of intracellular degradation could not be inhibited by colchicine or cytochalasin B, inhibitors of microtubular and microfilament func...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Berg, Richard A., Schwartz, Martin L., Crystal, Ronald G.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1980
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4746
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