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Regulation of the production of secretory proteins: Intracellular degradation of newly synthesized “defective” collagen

Confluent cultures of human fetal lung fibroblasts degrade approximately 10% of their newly synthesized collagen within the cell prior to secretion. This basal level of intracellular degradation could not be inhibited by colchicine or cytochalasin B, inhibitors of microtubular and microfilament func...

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發表在:Proc Natl Acad Sci U S A
Principais autores: Berg, Richard A., Schwartz, Martin L., Crystal, Ronald G.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 1980
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4746
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