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Regulation of the production of secretory proteins: Intracellular degradation of newly synthesized “defective” collagen

Confluent cultures of human fetal lung fibroblasts degrade approximately 10% of their newly synthesized collagen within the cell prior to secretion. This basal level of intracellular degradation could not be inhibited by colchicine or cytochalasin B, inhibitors of microtubular and microfilament func...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Berg, Richard A., Schwartz, Martin L., Crystal, Ronald G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1980
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349923/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933520/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.8.4746
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