S-adenosylmethionine decarboxylase overexpression inhibits mouse skin tumor promotion

Neoplastic growth is associated with increased polyamine biosynthetic activity and content. Tumor promoter treatment induces the rate-limiting enzymes in polyamine biosynthesis, ornithine decarboxylase (ODC), and S-adenosylmethionine decarboxylase (AdoMetDC), and targeted ODC overexpression is suffi...

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Autors principals: Shi, Chenxu, Cooper, Timothy K., McCloskey, Diane E., Glick, Adam B., Shantz, Lisa M., Feith, David J.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499050/
https://ncbi.nlm.nih.gov/pubmed/22610166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs184
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