Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis

It has been postulated that prostatic carcinogenesis is androgen dependent and that androgens mediate their effects primarily through epithelial cells; however, definitive proof of androgen hormone action in prostate cancer (PRCA) progression is lacking. Here we demonstrate through genetic loss of f...

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Autori principali: Ricke, Emily A., Williams, Karin, Lee, Yi-Fen, Couto, Suzana, Wang, Yuzhuo, Hayward, Simon W., Cunha, Gerald R., Ricke, William A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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None
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499049/
https://ncbi.nlm.nih.gov/pubmed/22535887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs153
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