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Androgen hormone action in prostatic carcinogenesis: stromal androgen receptors mediate prostate cancer progression, malignant transformation and metastasis

It has been postulated that prostatic carcinogenesis is androgen dependent and that androgens mediate their effects primarily through epithelial cells; however, definitive proof of androgen hormone action in prostate cancer (PRCA) progression is lacking. Here we demonstrate through genetic loss of f...

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Detalhes bibliográficos
Main Authors: Ricke, Emily A., Williams, Karin, Lee, Yi-Fen, Couto, Suzana, Wang, Yuzhuo, Hayward, Simon W., Cunha, Gerald R., Ricke, William A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499049/
https://ncbi.nlm.nih.gov/pubmed/22535887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs153
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