Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer

Meat mutagens, including heterocyclic amines (HCAs), polycyclic aromatic hydrocarbons (PAHs) and N-nitroso compounds (NOCs), may be involved in colorectal carcinogenesis depending on their activation or detoxification by phase I and II xenobiotic metabolizing enzymes (XME). Using unconditional logis...

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Detalhes bibliográficos
Main Authors: Gilsing, Anne M.J., Berndt, Sonja I, Ruder, Elizabeth 
H, Graubard, Barry I, Ferrucci, Leah M, Burdett, Laura, Weissfeld, Joel L., Cross, Amanda J, Sinha, Rashmi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3499048/
https://ncbi.nlm.nih.gov/pubmed/22552404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs158
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