Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine

Individual genes can be targeted with siRNAs. The use of nucleic acid nanoparticles (NPs) is a convenient method for delivering combinations of specific siRNAs in an organized and programmable manner. We present three assembly protocols to produce two different types of RNA self-assembling functiona...

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Autori principali: Afonin, Kirill A, Grabow, Wade W, Walker, Faye M, Bindewald, Eckart, Dobrovolskaia, Marina A, Shapiro, Bruce A, Jaeger, Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498981/
https://ncbi.nlm.nih.gov/pubmed/22134126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.418
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