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Design and self-assembly of siRNA-functionalized RNA nanoparticles for use in automated nanomedicine
Individual genes can be targeted with siRNAs. The use of nucleic acid nanoparticles (NPs) is a convenient method for delivering combinations of specific siRNAs in an organized and programmable manner. We present three assembly protocols to produce two different types of RNA self-assembling functiona...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498981/ https://ncbi.nlm.nih.gov/pubmed/22134126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.418 |
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