Caricamento...

Co-transcriptional Assembly of Chemically Modified RNA Nanoparticles Functionalized with siRNAs

[Image: see text] We report a generalized methodology for the one-pot production of chemically modified functional RNA nanoparticles during in vitro transcription with T7 RNA polymerase. The efficiency of incorporation of 2′-fluoro-dNTP in the transcripts by the wild type T7 RNA polymerase dramatica...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Afonin, Kirill A., Kireeva, Maria, Grabow, Wade W., Kashlev, Mikhail, Jaeger, Luc, Shapiro, Bruce A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498980/
https://ncbi.nlm.nih.gov/pubmed/23016824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl302302e
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !