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Co-transcriptional Assembly of Chemically Modified RNA Nanoparticles Functionalized with siRNAs
[Image: see text] We report a generalized methodology for the one-pot production of chemically modified functional RNA nanoparticles during in vitro transcription with T7 RNA polymerase. The efficiency of incorporation of 2′-fluoro-dNTP in the transcripts by the wild type T7 RNA polymerase dramatica...
में बचाया:
| मुख्य लेखकों: | , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498980/ https://ncbi.nlm.nih.gov/pubmed/23016824 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl302302e |
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