Targeted Delivery of Self-Complementary Adeno-Associated Virus Serotype 9 to the Brain, Using Magnetic Resonance Imaging-Guided Focused Ultrasound

Noninvasive drug delivery to the brain remains a major challenge for the treatment of neurological disorders. Transcranial focused ultrasound combined with lipid-coated gas microspheres injected into the bloodstream has been shown to increase the permeability of the blood–brain barrier locally and t...

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Detalhes bibliográficos
Main Authors: Thévenot, Emmanuel, Jordão, Jessica F., O'Reilly, Meaghan A., Markham, Kelly, Weng, Ying-Qi, Foust, Kevin D., Kaspar, Brian K., Hynynen, Kullervo, Aubert, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498907/
https://ncbi.nlm.nih.gov/pubmed/22838844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2012.013
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