Amyloid-β plaque reduction, endogenous antibody delivery and glial activation by brain-targeted, transcranial focused ultrasound

Noninvasive, targeted drug delivery to the brain can be achieved using transcranial focused ultrasound (FUS), which transiently increases the permeability of the blood-brain barrier (BBB) for localized delivery of therapeutics from the blood to the brain. Previously, we have demonstrated that FUS ca...

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Detalhes bibliográficos
Main Authors: Jordão, Jessica F., Thévenot, Emmanuel, Markham-Coultes, Kelly, Scarcelli, Tiffany, Weng, Ying-Qi, Xhima, Kristiana, O’Reilly, Meaghan, Huang, Yuexi, McLaurin, JoAnne, Hynynen, Kullervo, Aubert, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000699/
https://ncbi.nlm.nih.gov/pubmed/23707300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.05.008
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