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Sirtuin-4 Modulates Sensitivity to Induction of the Mitochondrial Permeability Transition Pore
The sustained opening of the mitochondrial permeability transition pore (PTP) is a decisive event in the onset of irreversible cell injury. The PTP is modulated by numerous exogenous and endogenous effectors, including mitochondrial membrane potential, ions and metabolites. Mitochondrial sirtuins ha...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3498821/ https://ncbi.nlm.nih.gov/pubmed/23044393 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbabio.2012.09.016 |
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