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Separation of random fragments of DNA according to properties of their sequences.

The separation of DNA fragments by electrophoresis at high temperature in a denaturing gradient is independent of the length of the fragments. We have suggested that the basis of fragment separation is that each DNA molecule undergoes partial melting as it encounters a concentration of denaturants s...

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Detalhes bibliográficos
Main Authors: Fischer, S G, Lerman, L S
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC349855/
https://ncbi.nlm.nih.gov/pubmed/6254023
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