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Non-random DNA fragmentation in next-generation sequencing
Next Generation Sequencing (NGS) technology is based on cutting DNA into small fragments, and their massive parallel sequencing. The multiple overlapping segments termed “reads” are assembled into a contiguous sequence. To reduce sequencing errors, every genome region should be sequenced several doz...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970190/ https://ncbi.nlm.nih.gov/pubmed/24681819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04532 |
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