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A Method for Identification of the Methylation Level of CpG Islands From NGS Data

In the course of sample preparation for Next Generation Sequencing (NGS), DNA is fragmented by various methods. Fragmentation shows a persistent bias with regard to the cleavage rates of various dinucleotides. With the exception of CpG dinucleotides the previously described biases were consistent wi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Uroshlev, Leonid A., Abdullaev, Eldar T., Umarova, Iren R., Il’icheva, Irina A., Panchenko, Larisa A., Polozov, Robert V., Kondrashov, Fyodor A., Nechipurenko, Yury D., Grokhovsky, Sergei L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248081/
https://ncbi.nlm.nih.gov/pubmed/32451390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65406-1
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