A Method for Identification of the Methylation Level of CpG Islands From NGS Data

In the course of sample preparation for Next Generation Sequencing (NGS), DNA is fragmented by various methods. Fragmentation shows a persistent bias with regard to the cleavage rates of various dinucleotides. With the exception of CpG dinucleotides the previously described biases were consistent wi...

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Vydáno v:Sci Rep
Hlavní autoři: Uroshlev, Leonid A., Abdullaev, Eldar T., Umarova, Iren R., Il’icheva, Irina A., Panchenko, Larisa A., Polozov, Robert V., Kondrashov, Fyodor A., Nechipurenko, Yury D., Grokhovsky, Sergei L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7248081/
https://ncbi.nlm.nih.gov/pubmed/32451390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65406-1
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