Processing of human beta-globin mRNA precursor to mRNA is defective in three patients with beta+-thalassemia.

Nucleated bone marrow cells from normal individuals and from three patients with homozygous beta+-thalassemia were pulse-labeled with tritiated nucleosides. The processing of the newly synthesized globin mRNA precursors was monitored by inhibiting additional transcription with actinomycin D for 30 m...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Maquat, L E, Kinniburgh, A J, Beach, L R, Honig, G R, Lazerson, J, Ershler, W B, Ross, J
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1980
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.4287
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!