Processing of human beta-globin mRNA precursor to mRNA is defective in three patients with beta+-thalassemia.
Nucleated bone marrow cells from normal individuals and from three patients with homozygous beta+-thalassemia were pulse-labeled with tritiated nucleosides. The processing of the newly synthesized globin mRNA precursors was monitored by inhibiting additional transcription with actinomycin D for 30 m...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
1980
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349818/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6933479/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.4287 |
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