Involvement of Dynamin-Related Protein 1 in Free Fatty Acid-Induced INS-1-Derived Cell Apoptosis

Elevated extracellular free fatty acids (FFAs) can induce pancreatic beta cell apoptosis, thereby contributing to the pathogenesis of type 2 diabetes mellitus (T2D). Mitochondrial dysfunction has been implicated in FFA-induced beta cell apoptosis. However, molecular mechanisms linking mitochondrial...

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Detalhes bibliográficos
Main Authors: Peng, Liang, Men, Xiuli, Zhang, Wenjian, Wang, Haiyan, Xu, Shiqing, Fang, Qing, Liu, Honglin, Yang, Wenying, Lou, Jinning
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498159/
https://ncbi.nlm.nih.gov/pubmed/23166623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049258
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