TRB3 mediates advanced glycation end product-induced apoptosis of pancreatic β-cells through the protein kinase C β pathway

Advanced glycation end products (AGEs), which accumulate in the body during the development of diabetes, may be one of the factors leading to pancreatic β-cell failure and reduced β-cell mass. However, the mechanisms responsible for AGE-induced apoptosis remain unclear. This study identified the rol...

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Publicado no:Int J Mol Med
Main Authors: Wang, Meng, Zhang, Wenjian, Xu, Shiqing, Peng, Liang, Wang, Zai, Liu, Honglin, Fang, Qing, Deng, Tingting, Men, Xiuli, Lou, Jinning
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466392/
https://ncbi.nlm.nih.gov/pubmed/28534945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2017.2991
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