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Effect of Pullulan Nanoparticle Surface Charges on HSA Complexation and Drug Release Behavior of HSA-Bound Nanoparticles

Nanoparticle (NP) compositions such as hydrophobicity and surface charge are vital to determine the presence and amount of human serum albumin (HSA) binding. The HSA binding influences drug release, biocompatibility, biodistribution, and intercellular trafficking of nanoparticles (NPs). Here, we pre...

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Detalhes bibliográficos
Main Authors: Tao, Xiaojun, Zhang, Qiufang, Ling, Kai, Chen, Yicun, Yang, Wenzhi, Gao, Fenfei, Shi, Ganggang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498137/
https://ncbi.nlm.nih.gov/pubmed/23166632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049304
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