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Effects of Particle Hydrophobicity, Surface Charge, Media pH Value and Complexation with Human Serum Albumin on Drug Release Behavior of Mitoxantrone-Loaded Pullulan Nanoparticles

We prepared two types of cholesterol hydrophobically modified pullulan nanoparticles (CHP) and carboxyethyl hydrophobically modified pullulan nanoparticles (CHCP) substituted with various degrees of cholesterol, including 3.11, 6.03, 6.91 and 3.46 per polymer, and named CHP(−3.11), CHP(−6.03), CHP(−...

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Detalhes bibliográficos
Publicado no:Nanomaterials (Basel)
Main Authors: Tao, Xiaojun, Jin, Shu, Wu, Dehong, Ling, Kai, Yuan, Liming, Lin, Pingfa, Xie, Yongchao, Yang, Xiaoping
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302549/
https://ncbi.nlm.nih.gov/pubmed/28344259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano6010002
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