Effects of Particle Hydrophobicity, Surface Charge, Media pH Value and Complexation with Human Serum Albumin on Drug Release Behavior of Mitoxantrone-Loaded Pullulan Nanoparticles

We prepared two types of cholesterol hydrophobically modified pullulan nanoparticles (CHP) and carboxyethyl hydrophobically modified pullulan nanoparticles (CHCP) substituted with various degrees of cholesterol, including 3.11, 6.03, 6.91 and 3.46 per polymer, and named CHP(−3.11), CHP(−6.03), CHP(−...

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Pubblicato in:Nanomaterials (Basel)
Autori principali: Tao, Xiaojun, Jin, Shu, Wu, Dehong, Ling, Kai, Yuan, Liming, Lin, Pingfa, Xie, Yongchao, Yang, Xiaoping
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5302549/
https://ncbi.nlm.nih.gov/pubmed/28344259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano6010002
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