Interaction of Mitoxantrone-Loaded Cholesterol Modified Pullulan Nanoparticles with Human Serum Albumin and Effect on Drug Release

To clarify nanoparticle-protein interaction and their action characteristics, the interactions between MTO-CHP NPs and human serum albumin (HSA) were studied by isothermal titration calorimetry (ITC), fluorescence spectroscopy, dynamic light scattering (DLS), and circular dichroism spectroscopy (CD)...

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Detalhes bibliográficos
Main Authors: Liming Yuan, Bu Guo, Wu Zhong, Yu Nie, Xiaoyan Yao, Xiaofeng Peng, Rong Wang, Hongyuan Yu, Shanyi Yang, Chunlian He, Xiaojun Tao, Qiufang Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2019-01-01
Colecção:Journal of Nanomaterials
Acesso em linha:http://dx.doi.org/10.1155/2019/8036863
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