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Effect of Pullulan Nanoparticle Surface Charges on HSA Complexation and Drug Release Behavior of HSA-Bound Nanoparticles

Nanoparticle (NP) compositions such as hydrophobicity and surface charge are vital to determine the presence and amount of human serum albumin (HSA) binding. The HSA binding influences drug release, biocompatibility, biodistribution, and intercellular trafficking of nanoparticles (NPs). Here, we pre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tao, Xiaojun, Zhang, Qiufang, Ling, Kai, Chen, Yicun, Yang, Wenzhi, Gao, Fenfei, Shi, Ganggang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3498137/
https://ncbi.nlm.nih.gov/pubmed/23166632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049304
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