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Crystallization and preliminary diffraction studies of GIM-1, a class B carbapenem-hydrolyzing β-­lactamase

GIM-1 is a member of the class B carbapenemases (metallo-β-lactamases; MBLs) and has a wide spectrum of activity against carbapenems, penicillins and extended-spectrum cephalosporins, but not aztreonam. GIM-1 presents an enormous challenge to infection control, particularly in the eradication of Gra...

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Detalhes bibliográficos
Main Authors: Hong, Myoung-Ki, Lee, Jung Hun, Kwon, Dae Beom, Kim, Jin-Kwang, Tran, Thi-Huyen, Nguyen, Dinh-Duc, Jeong, Byeong Chul, Lee, Sang Hee, Kang, Lin-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497985/
https://ncbi.nlm.nih.gov/pubmed/23027753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112035695
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