Structural Basis for Carbapenem-Hydrolyzing Mechanisms of Carbapenemases Conferring Antibiotic Resistance

Carbapenems (imipenem, meropenem, biapenem, ertapenem, and doripenem) are β-lactam antimicrobial agents. Because carbapenems have the broadest spectra among all β-lactams and are primarily used to treat infections by multi-resistant Gram-negative bacteria, the emergence and spread of carbapenemases...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Jeon, Jeong Ho, Lee, Jung Hun, Lee, Jae Jin, Park, Kwang Seung, Karim, Asad Mustafa, Lee, Chang-Ro, Jeong, Byeong Chul, Lee, Sang Hee
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4463611/
https://ncbi.nlm.nih.gov/pubmed/25938965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms16059654
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